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1

L’importance de la qualité en Biotechnologie : le cas du 1er biosimilaire de l’EPO

J.-Y. Le Cotonnec, F. Lawny

Journal:

Néphrologie & Thérapeutique

Year:

2009

Language:

french

File:

PDF, 840 KB

french, 2009

2

Qu’est-ce qu’un biosimilaire ? Jusqu’où va la similarité ?

P. Gravel, J. -Y. Le Cotonnec

Journal:

Year:

2011

Language:

french

File:

PDF, 274 KB

french, 2011

3

Clinical Pharmacology of Recombinant Human Follicle-Stimulating Hormone. II. Single Doses and Steady State Pharmacokinetics

Jean-Yves le Cotonnec M.D., Ph.D., , Hervé Claude Porchet M.D., , Vanya Beltrami Ph.D., , Azhar Khan Ph.D., , Steeve Toon Ph.D., , Malcolm Rowland Ph.D.

Journal:

Fertility and Sterility

Year:

1998

Language:

english

File:

PDF, 103 KB

english, 1998

4

Systematically variable geometry and architecture of incised‐valley fills controlled by orbital forcing: A conceptual model from the Pennsylvanian Breathitt Group (Kentucky, USA)

Le Cotonnec, Aymeric, Ventra, Dario, Moscariello, Andrea, Hudson, Sam

Journal:

Sedimentology (Wiley)

Year:

2019

File:

PDF, 81.36 MB

2019

5

Clinical pharmacology of recombinant human luteinizing hormone: Part I. Pharmacokinetics after intravenous administration to healthy female volunteers and comparison with urinary human luteinizing hormone

Jean-Yves le Cotonnec, HervéClaude Porchet, Vanya Beltrami, Alain Munafo

Journal:

Fertility and Sterility

Year:

1998

Language:

english

File:

PDF, 811 KB

english, 1998

6

Pharmacokinetics of recombinant human luteinizing hormone after intravenous, intramuscular, and subcutaneous administration in monkeys and comparison with intravenous administration of pituitary human luteinizing hormone.

Porchet, H C, Le Cotonnec, J Y, Neuteboom, B, Canali, S, Zanolo, G

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1995

Language:

english

File:

PDF, 779 KB

english, 1995

7

Comprehensive Pharmacokinetics of Urinary Human Follicle Stimulating Hormone in Healthy Female Volunteers

J.-Y. le Cotonnec, H. C. Porchet, V. Beltrami, A. Khan, S. Toon, M. Rowland

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.21 MB

1995

8

Clinical pharmacology of recombinant human luteinizing hormone: Part II. Bioavailability of recombinant human luteinizing hormone assessed with an immunoassay and an in vitro bioassay

Jean-Yves le Cotonnec, HervéClaude Porchet, Vanya Beltrami, Alain Munafo

Journal:

Fertility and Sterility

Year:

1998

Language:

english

File:

PDF, 687 KB

english, 1998

9

Pharmacokinetic and pharmacodynamic interactions between recombinant human luteinizing hormone and recombinant human follicle-stimulating hormone

Jean-Yves le Cotonnec, Ernest Loumaye, HervéClaude Porchet, Vanya Beltrami, Alain Munafo

Journal:

Fertility and Sterility

Year:

1998

Language:

english

File:

PDF, 1.03 MB

english, 1998

10

Clinical pharmacology of recombinant human follicle-stimulating hormone. III. Pharmacokinetic-pharmacodynamic modeling after repeated subcutaneous administration**Supported by grant GF 5117 from Ares Serono.††Presented in part at the 9th Annual Meeting of the European Society of Human Reproduction and Embriology, Thessaloniki, Greece, June 27 to 30, 1993.

Porchet, Hervé Claude, le Cotonnec, Jean-Yves, Loumaye, Ernest

Journal:

Fertility and Sterility

Year:

1994

Language:

english

File:

PDF, 1.29 MB

english, 1994

11

A Comparison of Parametric Classification Procedures of Remotely Sensed Data Applied on Different Landscape Units

L. Hubert-Moy, A. Cotonnec, L. Le Du, A. Chardin, P. Perez

Journal:

Remote Sensing of Environment

Year:

2001

Language:

english

File:

PDF, 1.88 MB

english, 2001

12

Clinical pharmacology of recombinant human follicle-stimulating hormone. II. Single doses and steady state pharmacokinetics**Supported by grant GF 5117 from Ares Serono, Geneva, Switzerland.††Presented in part at the 9th Annual Meeting of the European Society of Human Reproduction and Embriology, Thessaloniki, Greece, June 27 to 30, 1993.

Cotonnec, Jean-Yves le, Porchet, Hervé Claude, Beltrami, Vanya, Khan, Azhar, Toon, Steeve, Rowland, Malcolm

Journal:

Fertility and Sterility

Year:

1994

Language:

english

File:

PDF, 1.19 MB

english, 1994

13

No effect of food on single dose bioavailability of sustained release theophylline ( Sabidal); a comparison between Sabidal and choline theophyllinate solution

Jonkman, J.H.G., van der Boon, W.J.V., Balant, L.P., Le Cotonnec, J.Y.

Journal:

International Journal of Pharmaceutics

Year:

1985

Language:

english

File:

PDF, 289 KB

english, 1985

14

Biosimilar rhG-CSFs: how similar are they?

Patricia Gravel, Aarti Naik, Jean-Yves Le Cotonnec

Journal:

Targeted Oncology

Year:

2012

Language:

english

File:

PDF, 581 KB

english, 2012

15

Clinical Pharmacology of Recombinant Human Follicle-Stimulating Hormone (FSH). I. Comparative Pharmacokinetics with Urinary Human FSH

Jean-Yves le Cotonnec M.D., Ph.D., , Hervé Claude Porchet M.D., , Vanya Beltrami Ph.D., , Azhar Khan Ph.D., , Steeve Toon Ph.D., , Malcolm Rowland Ph.D.

Journal:

Fertility and Sterility

Year:

1998

Language:

english

File:

PDF, 121 KB

english, 1998

16

Clinical pharmacology of recombinant human follicle-stimulating hormone (FSH). I. Comparative pharmacokinetics with urinary human FSH**Supported by grant GF 5007 from Ares Serono, Geneva, Switzerland.††Presented in part at the 9th Annual Meeting of the European Society of Human Reproduction and Embriology, Thessaloniki, Greece, June 27 to 30, 1993.

Cotonnec, Jean-Yves le, Porchet, Hervé Claude, Beltrami, Vanya, Khan, Azhar, Toon, Steeve, Rowland, Malcolm

Journal:

Fertility and Sterility

Year:

1994

Language:

english

File:

PDF, 1.56 MB

english, 1994

17

Endocrinology: Comparative pharmacokinetics of two urinary human follicle stimulating hormone preparations in healthy female and male volunteers

le Cotonnec, Jean-Yves, Porchet, Hervé C., Beltrami, Vanya, Howles, Colin

Journal:

Human Reproduction

Year:

1993

Language:

english

File:

PDF, 806 KB

english, 1993

18

Pharmacokinetics and Pharmacodynamics of Recombinant Human Interferon-β in Healthy Male Volunteers

SALMON, P., LE COTONNEC, J.-Y., GALAZKA, A., ABDUL-AHAD, A., DARRAGH, A.

Journal:

Journal of Interferon & Cytokine Research

Year:

1996

Language:

english

File:

PDF, 992 KB

english, 1996

19

Clinical Pharmacology of Recombinant Human Follicle-Stimulating Hormone. III. Pharmacokinetic-Pharmacodynamic Modeling After Repeated Subcutaneous Administration

Hervé Claude Porchet M.D., Jean-Yves le Cotonnec M.D., Ph.D., Ernest Loumaye M.D., Ph.D.

Journal:

Fertility and Sterility

Year:

1998

Language:

english

File:

PDF, 165 KB

english, 1998

20

Modeling a bivariate control system: LH and testosterone response to the GnRH antagonist antide

Fattinger, K. E., Verotta, D., Porchet, H. C., Munafo, A., Le Cotonnec, J. Y., Sheiner, L. B.

Journal:

American Journal of Physiology-Endocrinology and Metabolism

Year:

1996

Language:

english

File:

PDF, 2.49 MB

english, 1996

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